Polpharma,Pyralgina 500mg 12

“Compound
Active ingredient: metamizole sodium (Metamizolum natricum).
1 tablet contains metamizole sodium monohydrate 500 mg.
Excipients: potato starch, gelatin, magnesium stearate.

Dosage
Medicine for oral administration.
The tablets should be taken with plenty of water.
Take the medicine with or after meals.
Adults: recurrent pain and fever: 1 tablet (500 mg) to 2 tablets (1000 mg).
The maximum single dose is 2 tablets (1000 mg of metamizole).
The maximum daily dose is 6 tablets (3000 mg of metamizole).
You should not use the medicine for longer than 3-5 days without consulting a doctor.
The dosage of the drug should be adjusted in the following cases:
elderly patients, people with reduced creatinine clearance,
liver and kidney dysfunction.

Action
Piralgin contains metamizole sodium, which has an analgesic, antipyretic and antispasmodic effect on smooth muscles. Metamizole belongs to the non-opioid analgesics from the group of pyrazolone derivatives.

Indications
Severe pain of various origins, increased body temperature, when the use of other measures is contraindicated or ineffective.

Contraindications
When you should not use Piralgin:
if you are allergic to metamizole, other pyrazolone and pyrazolidine derivatives (such as propyphenazone, phenazone or phenylbutazone) or any other ingredient of this medicine;
if you suffer from analgesic asthma syndrome or a known intolerance to pain medications such as urticaria, angioedema (swelling of the tongue, face, lips and/or throat), i.e. patients who react with bronchospasm or other anaphylactoid reaction to salicylates, paracetamol or other non-opioid pain relievers, including non-al anti-inflammatory drugs (NSAIDs),
if you have problems with your bone marrow (for example, after taking medications that reduce your body’s immunity) or changes in your blood counts, such as a decrease in the total number of white blood cells (leukopenia) or a certain type of white blood cell
granulocytes (agranulocytosis) or anemia;
if you suffer from acute renal or liver failure, acute hepatic porphyria;
if you have congenital glucose-6-phosphate dehydrogenase deficiency (a rare hereditary disease);
if you are taking a drug from the group of pyrazolone and pyrazolidine derivatives (for example, phenylbutazone, propyphenazone);
if you are pregnant or breastfeeding.”

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