- Therapeutic indications
Doloproct Rectal Cream is used for the symptomatic resolution of pain and inflammation in adults in the case of haemorrhoidal diseases, uninfected proctitis and anal eczema.
- Dosage and Posology
The drug should be taken according to the following doses and methods: Doloproct rectal cream should be applied twice a day, in the morning and in the evening (up to about 1 g of cream per application). In the first few days of treatment, it can be applied three times a day. To improve symptoms, only one application per day is often sufficient. The total duration of treatment should not exceed 2 weeks.
Doloproct is not recommended for use in children below 18 years of age due to a lack of data on safety and efficacy.
It is advisable to apply Doloproct after defecation. The anal region must be thoroughly cleansed before application. Apply a finger-tip unit of Doloproct rectal cream in the anal region using the tip of the finger to overcome the resistance of the sphincter. A finger-tip unit is the amount of rectal cream squeezed out of the tube and applied to the phalanx surface of an adult’s index finger. If Doloproct rectal cream is to be applied inside the rectum, screw the supplied applicator onto the tube and insert the end into the anus. A small amount of cream can then be applied by exerting gentle pressure on the tube.
- Overdose
The results of the acute toxicity studies conducted on the active substances of Doloproct show that there is no risk of developing acute toxic symptoms following an accidental overdose after a single rectal or perianal application of Doloproct. Following accidental ingestion of the preparation (for example in the case of ingestion of several grams of cream), the main foreseeable symptoms are the systemic ones attributable to lidocaine hydrochloride which, depending on the dose, can manifest themselves in the form of severe cardiovascular symptoms (depression of the cardiac function or, in extreme cases, cardiac arrest), or central nervous system symptoms (convulsions, dyspnoea or, in extreme cases, respiratory failure).
Treatment of an overdose includes careful monitoring of vital functions, supportive actions including oxygen administration and symptomatic treatment of central and cardiovascular disorders, eg with short-acting barbiturates, betasympathomimetics, atropine. Dialysis is of little use.
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